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Transmembrane Interactions of Full-length Mammalian Bitopic Cytochrome-P450-Cytochrome-b(5) Complex in Lipid Bilayers Revealed by Sensitivity-Enhanced Dynamic Nuclear Polarization Solid-state NMR Spectroscopy
The dynamic protein-protein and protein-ligand interactions of integral bitopic membrane proteins with a single membrane-spanning helix play a plethora of vital roles in the cellular processes associated with human health and diseases, including signaling and enzymatic catalysis. While an increasing...
Autores principales: | Yamamoto, Kazutoshi, Caporini, Marc A., Im, Sang-Choul, Waskell, Lucy, Ramamoorthy, Ayyalusamy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482851/ https://www.ncbi.nlm.nih.gov/pubmed/28646173 http://dx.doi.org/10.1038/s41598-017-04219-1 |
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