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Aberrant activation of the human sex-determining gene in early embryonic development results in postnatal growth retardation and lethality in mice
Sexual dimorphisms are prevalent in development, physiology and diseases in humans. Currently, the contributions of the genes on the male-specific region of the Y chromosome (MSY) in these processes are uncertain. Using a transgene activation system, the human sex-determining gene hSRY is activated...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482865/ https://www.ncbi.nlm.nih.gov/pubmed/28646221 http://dx.doi.org/10.1038/s41598-017-04117-6 |