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Increased glomerular filtration rate and impaired contractile function of mesangial cells in TRPC6 knockout mice

The present study was conducted to determine if TRPC6 regulates glomerular filtration rate (GFR) and the contractile function of glomerular mesangial cells (MCs). GFR was assessed in conscious TRPC6 wild type and knockout mice, and in anesthetized rats with and without in vivo knockdown of TRPC6 in...

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Detalles Bibliográficos
Autores principales:	Li, Weizu, Ding, Yanfeng, Smedley, Crystal, Wang, Yanxia, Chaudhari, Sarika, Birnbaumer, Lutz, Ma, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482875/ https://www.ncbi.nlm.nih.gov/pubmed/28646178 http://dx.doi.org/10.1038/s41598-017-04067-z

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