ChIP-seq analysis of genomic binding regions of five major transcription factors highlights a central role for ZIC2 in the mouse epiblast stem cell gene regulatory network

To obtain insight into the transcription factor (TF)-dependent regulation of epiblast stem cells (EpiSCs), we performed ChIP-seq analysis of the genomic binding regions of five major TFs. Analysis of in vivo biotinylated ZIC2, OTX2, SOX2, POU5F1 and POU3F1 binding in EpiSCs identified several new fe...

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Detalles Bibliográficos
Autores principales: Matsuda, Kazunari, Mikami, Tomoyuki, Oki, Shinya, Iida, Hideaki, Andrabi, Munazah, Boss, Jeremy M., Yamaguchi, Katsushi, Shigenobu, Shuji, Kondoh, Hisato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482983/
https://www.ncbi.nlm.nih.gov/pubmed/28455373
http://dx.doi.org/10.1242/dev.143479

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