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Immunogenicity and protective efficacy of a Salmonella Enteritidis sptP mutant as a live attenuated vaccine candidate

BACKGROUND: Salmonella enterica serovar Enteritidis (S. Enteritidis) is a highly adaptive pathogen in both humans and animals. As a Salmonella Type III secretion system (T3SS) effector, Salmonella protein tyrosine phosphatase (SptP) is critical for virulence in this genus. To investigate the feasibi...

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Detalles Bibliográficos
Autores principales: Lin, Zhijie, Tang, Peipei, Jiao, Yang, Kang, Xilong, Li, Qiuchun, Xu, Xiulong, Sun, Jun, Pan, Zhiming, Jiao, Xinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483252/
https://www.ncbi.nlm.nih.gov/pubmed/28646853
http://dx.doi.org/10.1186/s12917-017-1115-3

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