Detection of the Plasmodium falciparum Kelch-13 gene P553L mutation in sporozoites isolated from mosquito salivary glands in South-Central Vietnam

BACKGROUND: Plasmodium falciparum has developed resistance against artemisinin in Southeast Asia. Mutations in the P. falciparum Kelch-13 (Pfk13) gene are associated with artemisinin resistance in vitro and in vivo. We investigated the prevalence of mutations in PfK13 from sporozoite-stage parasites...

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Detalles Bibliográficos
Autores principales: Maeno, Yoshimasa, Quang, Nguyen Tuyen, Culleton, Richard, Kawai, Satoru, Masuda, Gaku, Hori, Kaoru, Nakazawa, Shusuke, Marchand, Ron P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483274/
https://www.ncbi.nlm.nih.gov/pubmed/28646896
http://dx.doi.org/10.1186/s13071-017-2247-9

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