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Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination

BACKGROUND: Antibodies with specificity for myelin oligodendrocyte glycoprotein (MOG) are implicated in multiple sclerosis and related diseases. The pathogenic importance of anti-MOG antibody in primary demyelinating pathology remains poorly characterized. OBJECTIVE: The objective of this study is t...

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Detalles Bibliográficos
Autores principales: Berg, Carsten Tue, Khorooshi, Reza, Asgari, Nasrin, Owens, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483301/
https://www.ncbi.nlm.nih.gov/pubmed/28646890
http://dx.doi.org/10.1186/s12974-017-0899-1