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Rapid creation of BAC-based human artificial chromosome vectors by transposition with synthetic alpha-satellite arrays
Efficient construction of BAC-based human artificial chromosomes (HACs) requires optimization of each key functional unit as well as development of techniques for the rapid and reliable manipulation of high-molecular weight BAC vectors. Here, we have created synthetic chromosome 17-derived alpha-sat...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548352/ https://www.ncbi.nlm.nih.gov/pubmed/15673719 http://dx.doi.org/10.1093/nar/gki207 |