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The mystery behind membrane insertion: a review of the complement membrane attack complex

The membrane attack complex (MAC) is an important innate immune effector of the complement terminal pathway that forms cytotoxic pores on the surface of microbes. Despite many years of research, MAC structure and mechanism of action have remained elusive, relying heavily on modelling and inference f...

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Detalles Bibliográficos
Autores principales: Bayly-Jones, Charles, Bubeck, Doryen, Dunstone, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483522/
https://www.ncbi.nlm.nih.gov/pubmed/28630159
http://dx.doi.org/10.1098/rstb.2016.0221