Cargando…
Suppression of nonsense-mediated mRNA decay permits unbiased gene trapping in mouse embryonic stem cells
An international collaborative project has been proposed to inactivate all mouse genes in embryonic stem (ES) cells using a combination of random and targeted insertional mutagenesis techniques. Random gene trapping will be the first choice in the initial phase, and gene-targeting experiments will t...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548380/ https://www.ncbi.nlm.nih.gov/pubmed/15687378 http://dx.doi.org/10.1093/nar/gni022 |