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Suppression of nonsense-mediated mRNA decay permits unbiased gene trapping in mouse embryonic stem cells

An international collaborative project has been proposed to inactivate all mouse genes in embryonic stem (ES) cells using a combination of random and targeted insertional mutagenesis techniques. Random gene trapping will be the first choice in the initial phase, and gene-targeting experiments will t...

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Detalles Bibliográficos
Autores principales: Shigeoka, Toshiaki, Kawaichi, Masashi, Ishida, Yasumasa
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548380/
https://www.ncbi.nlm.nih.gov/pubmed/15687378
http://dx.doi.org/10.1093/nar/gni022

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