Cargando…
Suppression of nonsense-mediated mRNA decay permits unbiased gene trapping in mouse embryonic stem cells
An international collaborative project has been proposed to inactivate all mouse genes in embryonic stem (ES) cells using a combination of random and targeted insertional mutagenesis techniques. Random gene trapping will be the first choice in the initial phase, and gene-targeting experiments will t...
Autores principales: | Shigeoka, Toshiaki, Kawaichi, Masashi, Ishida, Yasumasa |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548380/ https://www.ncbi.nlm.nih.gov/pubmed/15687378 http://dx.doi.org/10.1093/nar/gni022 |
Ejemplares similares
-
Mixture of differentially tagged Tol2 transposons accelerates conditional disruption of a broad spectrum of genes in mouse embryonic stem cells
por: Mayasari, N. Ika, et al.
Publicado: (2012) -
Evidence that the Upf1-related molecular motor scans the 3′-UTR to ensure mRNA integrity
por: Shigeoka, Toshiaki, et al.
Publicado: (2012) -
A GFP-based reporter system to monitor nonsense-mediated mRNA decay
por: Paillusson, Alexandra, et al.
Publicado: (2005) -
Collection of homozygous mutant mouse embryonic stem cells arising from autodiploidization during haploid gene trap mutagenesis
por: Yamanishi, Ayako, et al.
Publicado: (2018) -
Enhanced gene trapping in mouse embryonic stem cells
por: Schnütgen, Frank, et al.
Publicado: (2008)