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Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer
BACKGROUND: Metastatic clear cell renal cell cancer (mccRCC) portends a poor prognosis and urgently requires better clinical tools for prognostication as well as for prediction of response to treatment. Considerable investment in molecular risk stratification has sought to overcome the performance c...
Autores principales: | Lubbock, Alexander L. R., Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Mullen, Peter, O’Donnell, Marie, Powles, Thomas, Harrison, David J., Overton, Ian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483837/ https://www.ncbi.nlm.nih.gov/pubmed/28648142 http://dx.doi.org/10.1186/s12916-017-0874-9 |
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