Multi-site binding of epigallocatechin gallate to human serum albumin measured by NMR and isothermal titration calorimetry

The affinity of epigallocatechin gallate (EGCG) for human serum albumin (HSA) was measured in physiological conditions using NMR and isothermal titration calorimetry (ITC). NMR estimated the K(a) (self-dissociation constant) of EGCG as 50 mM. NMR showed two binding events: strong (n(1)=1.8 ± 0.2; K(...

Descripción completa

Detalles Bibliográficos
Autores principales: Eaton, Joshua D., Williamson, Mike P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484023/
https://www.ncbi.nlm.nih.gov/pubmed/28424370
http://dx.doi.org/10.1042/BSR20170209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484023/
https://www.ncbi.nlm.nih.gov/pubmed/28424370
http://dx.doi.org/10.1042/BSR20170209

Ejemplares similares