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Clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning and prognosis analysis after rescue

This study reports the clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning, and analyzes the prognosis after rescue. The general data of 68 patients with severe organophosphorus poisoning treated in our hospital were retrospectively analyzed. These patients we...

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Autores principales: Dong, Hui, Weng, Yi-Bing, Zhen, Gen-Shen, Li, Feng-Jie, Jin, Ai-Chun, Liu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484230/
https://www.ncbi.nlm.nih.gov/pubmed/28640122
http://dx.doi.org/10.1097/MD.0000000000007237
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author Dong, Hui
Weng, Yi-Bing
Zhen, Gen-Shen
Li, Feng-Jie
Jin, Ai-Chun
Liu, Jie
author_facet Dong, Hui
Weng, Yi-Bing
Zhen, Gen-Shen
Li, Feng-Jie
Jin, Ai-Chun
Liu, Jie
author_sort Dong, Hui
collection PubMed
description This study reports the clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning, and analyzes the prognosis after rescue. The general data of 68 patients with severe organophosphorus poisoning treated in our hospital were retrospectively analyzed. These patients were divided into 2 groups: treatment group, and control group. Patients in the control group received routine emergency treatment, while patients in the treatment group additionally received hemoperfusion plus hemodialysis on the basis of routine emergency treatment. The curative effects in these 2 groups and the prognosis after rescue were compared. Compared with the control group, atropinization time, recovery time of cholinesterase activity, recovery time of consciousness, extubation time, and length of hospital stay were shorter (P < .05); the total usage of atropine was significantly lower (P < .05); Glasgow Coma Score was significantly higher (P < .05); acute physiology and chronic health score (APACHE II) was significantly lower (P < .05); and mortality and poisoning rebound rate was significantly lower (P < .05) in the treatment group. Hemoperfusion and hemodialysis on the basis of routine emergency treatment for critical patients with organophosphorus poisoning can improve rescue outcomes and improve the prognosis of patients, which should be popularized.
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spelling pubmed-54842302017-07-06 Clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning and prognosis analysis after rescue Dong, Hui Weng, Yi-Bing Zhen, Gen-Shen Li, Feng-Jie Jin, Ai-Chun Liu, Jie Medicine (Baltimore) 3900 This study reports the clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning, and analyzes the prognosis after rescue. The general data of 68 patients with severe organophosphorus poisoning treated in our hospital were retrospectively analyzed. These patients were divided into 2 groups: treatment group, and control group. Patients in the control group received routine emergency treatment, while patients in the treatment group additionally received hemoperfusion plus hemodialysis on the basis of routine emergency treatment. The curative effects in these 2 groups and the prognosis after rescue were compared. Compared with the control group, atropinization time, recovery time of cholinesterase activity, recovery time of consciousness, extubation time, and length of hospital stay were shorter (P < .05); the total usage of atropine was significantly lower (P < .05); Glasgow Coma Score was significantly higher (P < .05); acute physiology and chronic health score (APACHE II) was significantly lower (P < .05); and mortality and poisoning rebound rate was significantly lower (P < .05) in the treatment group. Hemoperfusion and hemodialysis on the basis of routine emergency treatment for critical patients with organophosphorus poisoning can improve rescue outcomes and improve the prognosis of patients, which should be popularized. Wolters Kluwer Health 2017-06-23 /pmc/articles/PMC5484230/ /pubmed/28640122 http://dx.doi.org/10.1097/MD.0000000000007237 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle 3900
Dong, Hui
Weng, Yi-Bing
Zhen, Gen-Shen
Li, Feng-Jie
Jin, Ai-Chun
Liu, Jie
Clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning and prognosis analysis after rescue
title Clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning and prognosis analysis after rescue
title_full Clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning and prognosis analysis after rescue
title_fullStr Clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning and prognosis analysis after rescue
title_full_unstemmed Clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning and prognosis analysis after rescue
title_short Clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning and prognosis analysis after rescue
title_sort clinical emergency treatment of 68 critical patients with severe organophosphorus poisoning and prognosis analysis after rescue
topic 3900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484230/
https://www.ncbi.nlm.nih.gov/pubmed/28640122
http://dx.doi.org/10.1097/MD.0000000000007237
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