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An ancestral haplotype of the human PERIOD2 gene associates with reduced sensitivity to light-induced melatonin suppression
Humans show various responses to the environmental stimulus in individual levels as “physiological variations.” However, it has been unclear if these are caused by genetic variations. In this study, we examined the association between the physiological variation of response to light-stimulus and gen...
Autores principales: | Akiyama, Tokiho, Katsumura, Takafumi, Nakagome, Shigeki, Lee, Sang-il, Joh, Keiichiro, Soejima, Hidenobu, Fujimoto, Kazuma, Kimura, Ryosuke, Ishida, Hajime, Hanihara, Tsunehiko, Yasukouchi, Akira, Satta, Yoko, Higuchi, Shigekazu, Oota, Hiroki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484468/ https://www.ncbi.nlm.nih.gov/pubmed/28650999 http://dx.doi.org/10.1371/journal.pone.0178373 |
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