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Interferon signaling in Peromyscus leucopus confers a potent and specific restriction to vector-borne flaviviruses
Tick-borne flaviviruses (TBFVs), including Powassan virus and tick-borne encephalitis virus cause encephalitis or hemorrhagic fevers in humans with case-fatality rates ranging from 1–30%. Despite severe disease in humans, TBFV infection of natural rodent hosts has little noticeable effect. Currently...
Autores principales: | Izuogu, Adaeze O., McNally, Kristin L., Harris, Stephen E., Youseff, Brian H., Presloid, John B., Burlak, Christopher, Munshi-South, Jason, Best, Sonja M., Taylor, R. Travis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484488/ https://www.ncbi.nlm.nih.gov/pubmed/28650973 http://dx.doi.org/10.1371/journal.pone.0179781 |
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