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Epigenetic adaptation of the placental serotonin transporter gene (SLC6A4) to gestational diabetes mellitus

We tested the hypothesis that gestational diabetes mellitus (GDM) alters the DNA methylation pattern of the fetal serotonin transporter gene (SLC6A4), and examined the functional relevance of DNA methylation for regulation of the SLC6A4 expression in the human placenta. The study included 50 mother-...

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Detalles Bibliográficos
Autores principales: Blazevic, Sofia, Horvaticek, Marina, Kesic, Maja, Zill, Peter, Hranilovic, Dubravka, Ivanisevic, Marina, Desoye, Gernot, Stefulj, Jasminka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484502/
https://www.ncbi.nlm.nih.gov/pubmed/28650965
http://dx.doi.org/10.1371/journal.pone.0179934

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