Cargando…
Exacerbation of Japanese Encephalitis by CD11c(hi) Dendritic Cell Ablation Is Associated with an Imbalance in Regulatory Foxp3(+) and IL-17(+)CD4(+) Th17 Cells and in Ly-6C(hi) and Ly-6C(lo) Monocytes
Japanese encephalitis (JE) is neuroinflammation characterized by uncontrolled infiltration of peripheral leukocytes into the central nervous system (CNS). We previously demonstrated exacerbation of JE following CD11c(hi) dendritic cell (DC) ablation in CD11c-DTR transgenic mice. Moreover, CD11c(hi)...
Autores principales: | Choi, Jin Young, Kim, Jin Hyoung, Patil, Ajit Mahadev, Kim, Seong Bum, Uyangaa, Erdenebelig, Hossain, Ferdaus Mohd Altaf, Eo, Seong Kug |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Immunologists
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484650/ https://www.ncbi.nlm.nih.gov/pubmed/28680381 http://dx.doi.org/10.4110/in.2017.17.3.192 |
Ejemplares similares
-
CD11c(hi) Dendritic Cells Regulate Ly-6C(hi) Monocyte Differentiation to Preserve Immune-privileged CNS in Lethal Neuroinflammation
por: Kim, Jin Hyoung, et al.
Publicado: (2015) -
CCL2, but not its receptor, is essential to restrict immune privileged central nervous system‐invasion of Japanese encephalitis virus via regulating accumulation of CD11b(+) Ly‐6C(hi) monocytes
por: Kim, Jin Hyoung, et al.
Publicado: (2016) -
Amelioration of Japanese encephalitis by blockage of 4-1BB signaling is coupled to divergent enhancement of type I/II IFN responses and Ly-6C(hi) monocyte differentiation
por: Kim, Seong Bum, et al.
Publicado: (2015) -
CCR5 ameliorates Japanese encephalitis via dictating the equilibrium of regulatory CD4(+)Foxp3(+) T and IL-17(+)CD4(+) Th17 cells
por: Kim, Jin Hyoung, et al.
Publicado: (2016) -
Type I IFN signaling limits hemorrhage-like disease after infection with Japanese encephalitis virus through modulating a prerequisite infection of CD11b(+)Ly-6C(+) monocytes
por: Patil, Ajit Mahadev, et al.
Publicado: (2021)