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Intracellular targeting of annexin A2 inhibits tumor cell adhesion, migration, and in vivo grafting

Cytoskeletal-associated proteins play an active role in coordinating the adhesion and migration machinery in cancer progression. To identify functional protein networks and potential inhibitors, we screened an internalizing phage (iPhage) display library in tumor cells, and selected LGRFYAASG as a c...

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Detalles Bibliográficos
Autores principales: Staquicini, Daniela I., Rangel, Roberto, Guzman-Rojas, Liliana, Staquicini, Fernanda I., Dobroff, Andrey S., Tarleton, Christy A., Ozbun, Michelle A., Kolonin, Mikhail G., Gelovani, Juri G., Marchiò, Serena, Sidman, Richard L., Hajjar, Katherine A., Arap, Wadih, Pasqualini, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484684/
https://www.ncbi.nlm.nih.gov/pubmed/28652618
http://dx.doi.org/10.1038/s41598-017-03470-w