Self-diploidization of human haploid parthenogenetic embryos through the Rho pathway regulates endomitosis and failed cytokinesis

A diploid genome is necessary for normal mammalian development, thus haploid parthenogenetic embryos undergo frequent self-diploidization during preimplantation development; however, the underlying mechanism is unclear. In this study, time-lapse recording revealed that human haploid parthenotes (HPs...

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Detalles Bibliográficos
Autores principales: Leng, Lizhi, Ouyang, Qi, Kong, Xiangyi, Gong, Fei, Lu, Changfu, Zhao, Lei, Shi, Yun, Cheng, Dehua, Hu, Liang, Lu, Guangxiu, Lin, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484709/
https://www.ncbi.nlm.nih.gov/pubmed/28652594
http://dx.doi.org/10.1038/s41598-017-04602-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484709/
https://www.ncbi.nlm.nih.gov/pubmed/28652594
http://dx.doi.org/10.1038/s41598-017-04602-y

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