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Gga-miR-219b targeting BCL11B suppresses proliferation, migration and invasion of Marek’s disease tumor cell MSB1

Marek’s disease (MD), caused by Marek’s disease virus (MDV), is a lymphotropic neoplastic disease. Previous miRNAome analysis showed gga-miR-219b was significantly downregulated in MDV-induced lymphoma, and one of its potential target genes, B-cell chronic lymphocytic /lymphoma 11B (BCL11B) was pred...

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Detalles Bibliográficos
Autores principales: Zhao, Chunfang, Li, Xin, Han, Bo, You, Zhen, Qu, Lujiang, Liu, Changjun, Song, Jiuzhou, Lian, Ling, Yang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484716/
https://www.ncbi.nlm.nih.gov/pubmed/28652615
http://dx.doi.org/10.1038/s41598-017-04434-w