Cargando…

Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct

BACKGROUND AND AIMS: The effects of glucocorticoids on fuel metabolism are complex. Acute glucocorticoid excess promotes lipolysis but chronic glucocorticoid excess causes visceral fat accumulation. We hypothesized that interactions between cortisol and insulin and adrenaline account for these confl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stimson, Roland H., Anderson, Anna J., Ramage, Lynne E., Macfarlane, David P., de Beaux, Andrew C., Mole, Damian J., Andrew, Ruth, Walker, Brian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484992/ https://www.ncbi.nlm.nih.gov/pubmed/28177189 http://dx.doi.org/10.1111/dom.12899

Ejemplares similares

Effects of Proportions of Dietary Macronutrients on Glucocorticoid Metabolism in Diet-Induced Obesity in Rats
por: Stimson, Roland H., et al.
Publicado: (2010)

Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia
por: Alwashih, Mohammad A., et al.
Publicado: (2017)

Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation
por: Ramage, Lynne E., et al.
Publicado: (2016)

GDF15 Is Elevated in Conditions of Glucocorticoid Deficiency and Is Modulated by Glucocorticoid Replacement
por: Melvin, Audrey, et al.
Publicado: (2019)

SUN-221 Subclinical Alpha-1 Antitrypsin Deficiency Is Associated with Increased Free Cortisol Fraction in Plasma and Altered Glucocorticoid Delivery to Tissues
por: Boyle, Luke David, et al.
Publicado: (2020)

Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity
por: Morgan, Ruth A., et al.
Publicado: (2017)

Lack of regulation of 11β-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism
por: Sigurjonsdottir, Helga A, et al.
Publicado: (2009)

β-Cell-Specific Glucocorticoid Reactivation Attenuates Inflammatory β-Cell Destruction
por: Liu, Xiaoxia, et al.
Publicado: (2014)

Acute interaction between hydrocortisone and insulin alters the plasma metabolome in humans
por: Alwashih, Mohammad A., et al.
Publicado: (2017)

Take control of permissions in Leopard
por: Tanaka, Brian
Publicado: (2009)

Dysregulation of glucocorticoid metabolism in murine obesity: comparable effects of leptin resistance and deficiency
por: Livingstone, Dawn E W, et al.
Publicado: (2009)

FRI025 Succinate Receptor Activation Increases Respiration In Human But Not Murine Brown Adipocytes
por: McNeill, Ben T, et al.
Publicado: (2023)

Diet-induced weight loss alters hepatic glucocorticoid metabolism in type 2 diabetes mellitus
por: Stomby, Andreas, et al.
Publicado: (2020)

Metformin Increases Cortisol Regeneration by 11βHSD1 in Obese Men With and Without Type 2 Diabetes Mellitus
por: Anderson, Anna J., et al.
Publicado: (2016)

Bile acids modulate glucocorticoid metabolism and the hypothalamic–pituitary–adrenal axis in obstructive jaundice()
por: McNeilly, Alison D., et al.
Publicado: (2010)

SAT-009 Proof of Concept That Corticosterone Has a Higher Therapeutic Index Than Hydrocortisone in Patients with Congenital Adrenal Hyperplasia
por: Kyle, Catriona, et al.
Publicado: (2019)

Hypoxia-driven metabolic reprogramming of adipocytes fuels cancer cell proliferation
por: Aird, R., et al.
Publicado: (2022)

Permissive hypofiltration
por: Chawla, Lakhmir S, et al.
Publicado: (2012)

ABCC1 modulates negative feedback control of the hypothalamic-pituitary-adrenal axis in vivo in humans
por: Kyle, Catriona J., et al.
Publicado: (2022)

Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with Type 2 diabetes with and without fatty liver
por: Macfarlane, D. P., et al.
Publicado: (2014)

Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice
por: Mak, Tracy C S, et al.
Publicado: (2019)

Increased Whole-Body and Sustained Liver Cortisol Regeneration by 11β-Hydroxysteroid Dehydrogenase Type 1 in Obese Men With Type 2 Diabetes Provides a Target for Enzyme Inhibition
por: Stimson, Roland H., et al.
Publicado: (2011)

Quality of life in adults with congenital adrenal hyperplasia relates to glucocorticoid treatment, adiposity and insulin resistance: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE)
por: Han, Thang S, et al.
Publicado: (2013)

Arthritis and the role of endogenous glucocorticoids
por: Macfarlane, Eugenie, et al.
Publicado: (2020)

Growth behavior of bovine herpesvirus-1 in permissive and semi-permissive cells
por: Murata, Takayuki, et al.
Publicado: (1999)

Is physiological glucocorticoid replacement important in children?
por: Porter, John, et al.
Publicado: (2017)

Organic heterojunctions for direct solar fuel generation
por: Sprick, Reiner Sebastian, et al.
Publicado: (2020)

Effects of Obesity and Insulin on Tissue-Specific Recycling Between Cortisol and Cortisone in Men
por: Anderson, Anna J, et al.
Publicado: (2020)

Permission to Speak Freely
por: Kincaid, Matt
Publicado: (2017)

Susceptibility and Permissivity of Zebrafish (Danio rerio) Larvae to Cypriniviruses
por: Streiff, Cindy, et al.
Publicado: (2023)

Cortisol Release From Adipose Tissue by 11β-Hydroxysteroid Dehydrogenase Type 1 in Humans
por: Stimson, Roland H., et al.
Publicado: (2009)

Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides
por: Weir, Graeme, et al.
Publicado: (2018)

Does experience provide a permissive or instructive influence on the development of direction selectivity in visual cortex?
por: Roy, Arani, et al.
Publicado: (2018)

Propriety and permissiveness in bourbon Mexico /
por: Viqueira Albán, Juan Pedro
Publicado: (1999)

Permissive hypofiltration: an alternative view
por: Ricci, Zaccaria, et al.
Publicado: (2012)

Who Asks Permission for an Autopsy?
por: Chana, Jagdeep, et al.
Publicado: (1990)

Should We Be Permissive with Hypercapnia?
por: Nassar, Boulos
Publicado: (2022)

The permissive binding theory of cancer
por: Weisman, Caroline M.
Publicado: (2023)

Perceptions of the ethical permissibility of strict travel restrictions to mitigate transmission of SARS-CoV-2
por: Hartsock, Jane A., et al.
Publicado: (2022)

Species-specific regulation of angiogenesis by glucocorticoids reveals contrasting effects on inflammatory and angiogenic pathways
por: Morgan, Ruth, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_kgf03dj1utkjao5fuarqpgj83s