Cargando…
Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G‐quadruplex in K(+) Buffer
Selective G‐quadruplex ligands offer great promise for the development of anti‐cancer therapies. A novel series of divalent cationic naphthalene diimide ligands that selectively bind to the hybrid form of the human telomeric G‐quadruplex in K(+) buffer are described herein. We demonstrate that an im...
Autores principales: | Street, Steven T. G., Chin, Donovan N., Hollingworth, Gregory J., Berry, Monica, Morales, Juan C., Galan, M. Carmen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485019/ https://www.ncbi.nlm.nih.gov/pubmed/28257554 http://dx.doi.org/10.1002/chem.201700140 |
Ejemplares similares
-
Naphthalene Diimides as Multimodal G-Quadruplex-Selective Ligands
por: Pirota, Valentina, et al.
Publicado: (2019) -
Naphthalene Diimides Carrying Two β-Cyclodextrins Prefer Telomere RNA G-Quadruplex Recognition
por: Zou, Tingting, et al.
Publicado: (2022) -
G-Quadruplex
Identification in the Genome of
Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents
por: Belmonte-Reche, Efres, et al.
Publicado: (2018) -
A Selective G-Quadruplex DNA-Stabilizing Ligand Based on a Cyclic Naphthalene Diimide Derivative
por: Islam, Md. Monirul, et al.
Publicado: (2015) -
G-Quadruplex
DNA as a Target in Pathogenic
Bacteria: Efficacy of an Extended Naphthalene Diimide Ligand and Its
Mode of Action
por: Cebrián, Rubén, et al.
Publicado: (2021)