Mutagenicity testing with transgenic mice. Part II: Comparison with the mouse spot test

The mouse spot test, an in vivo mutation assay, has been used to assess a number of chemicals. It is at present the only in vivo mammalian test system capable of detecting somatic gene mutations according to OECD guidelines (OECD guideline 484). It is however rather insensitive, animal consuming and...

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Detalles Bibliográficos
Autores principales: Wahnschaffe, Ulrich, Bitsch, Annette, Kielhorn, Janet, Mangelsdorf, Inge
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548508/
https://www.ncbi.nlm.nih.gov/pubmed/15676065
http://dx.doi.org/10.1186/1477-3163-4-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548508/
https://www.ncbi.nlm.nih.gov/pubmed/15676065
http://dx.doi.org/10.1186/1477-3163-4-4

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