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Mutagenicity testing with transgenic mice. Part II: Comparison with the mouse spot test
The mouse spot test, an in vivo mutation assay, has been used to assess a number of chemicals. It is at present the only in vivo mammalian test system capable of detecting somatic gene mutations according to OECD guidelines (OECD guideline 484). It is however rather insensitive, animal consuming and...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548508/ https://www.ncbi.nlm.nih.gov/pubmed/15676065 http://dx.doi.org/10.1186/1477-3163-4-4 |