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Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches
Epigenetic and metabolic alterations in cancer cells are highly intertwined. Oncogene-driven metabolic rewiring modifies the epigenetic landscape via modulating the activities of DNA and histone modification enzymes at the metabolite level. Conversely, epigenetic mechanisms regulate the expression o...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485177/ https://www.ncbi.nlm.nih.gov/pubmed/28092669 http://dx.doi.org/10.1038/onc.2016.485 |