FOXM1 recruits nuclear Aurora kinase A to participate in a positive feedback loop essential for the self-renewal of breast cancer stem cells

Substantial evidence suggests that breast cancer initiation, recurrence and drug resistance is supported by breast cancer stem cells (BCSCs). Recently, we reported a novel role of Aurora kinase A (AURKA) in BCSCs, as a transactivating co-factor in the induction of the c-Myc oncoprotein. However, the...

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Detalles Bibliográficos
Autores principales: Yang, N, Wang, C, Wang, Z, Zona, S, Lin, S-X, Wang, X, Yan, M, Zheng, F-M, Li, S-S, Xu, B, Bella, L, Yong, J-S, Lam, E W-F, Liu, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485180/
https://www.ncbi.nlm.nih.gov/pubmed/28114286
http://dx.doi.org/10.1038/onc.2016.490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485180/
https://www.ncbi.nlm.nih.gov/pubmed/28114286
http://dx.doi.org/10.1038/onc.2016.490

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