Cargando…
FOXM1 recruits nuclear Aurora kinase A to participate in a positive feedback loop essential for the self-renewal of breast cancer stem cells
Substantial evidence suggests that breast cancer initiation, recurrence and drug resistance is supported by breast cancer stem cells (BCSCs). Recently, we reported a novel role of Aurora kinase A (AURKA) in BCSCs, as a transactivating co-factor in the induction of the c-Myc oncoprotein. However, the...
Autores principales: | Yang, N, Wang, C, Wang, Z, Zona, S, Lin, S-X, Wang, X, Yan, M, Zheng, F-M, Li, S-S, Xu, B, Bella, L, Yong, J-S, Lam, E W-F, Liu, Q |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485180/ https://www.ncbi.nlm.nih.gov/pubmed/28114286 http://dx.doi.org/10.1038/onc.2016.490 |
Ejemplares similares
-
FOXM1: An emerging master regulator of DNA damage response and genotoxic agent resistance
por: Zona, Stefania, et al.
Publicado: (2014) -
Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance
por: Nestal de Moraes, Gabriela, et al.
Publicado: (2016) -
FBW7-Aurora B-p53 feedback loop regulates mitosis and cell growth
por: Wang, Yifan, et al.
Publicado: (2012) -
Aurora-A promotes the establishment of spindle assembly checkpoint by priming the Haspin-Aurora-B feedback loop in late G2 phase
por: Yu, Fazhi, et al.
Publicado: (2017) -
Expression of FOXM1 and Aurora-A predicts prognosis and sorafenib efficacy in patients with hepatocellular carcinoma
por: Su, Wen-Lung, et al.
Publicado: (2020)