A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFα-TGFα-EGFR

Peritoneum is the most common site for ovarian cancer metastasis. Here we investigate how cancer epigenetics regulates reciprocal tumor-stromal interactions in peritoneal metastasis of ovarian cancer. Firstly, we find that omental stromal fibroblasts enhance colony formation of metastatic ovarian ca...

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Detalles Bibliográficos
Autores principales: Lau, T-S, Chan, L K-Y, Wong, E C-H, Hui, C W-C, Sneddon, K, Cheung, T-H, Yim, S-F, Lee, J H-S, Yeung, C S-Y, Chung, T K-H, Kwong, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485181/
https://www.ncbi.nlm.nih.gov/pubmed/28166193
http://dx.doi.org/10.1038/onc.2016.509

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