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Synaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant mice
BACKGROUND: In Leber's congenital amaurosis (LCA), affected individuals are blind, or nearly so, from birth. This early onset suggests abnormal development of the neural retina. Mutations in genes that affect the development and/or function of photoreceptor cells have been found to be responsib...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548520/ https://www.ncbi.nlm.nih.gov/pubmed/15676071 http://dx.doi.org/10.1186/1471-2202-6-5 |