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Mitochondrial transcription factor B2 is essential for mitochondrial and cellular function in pancreatic β-cells

OBJECTIVE: Insulin release from pancreatic β-cells is controlled by plasma glucose levels via mitochondrial fuel metabolism. Therefore, insulin secretion is critically dependent on mitochondrial DNA (mtDNA) and the genes it encodes. Mitochondrial transcription factor B2 (TFB2M) controls transcriptio...

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Detalles Bibliográficos
Autores principales:	Nicholas, Lisa M., Valtat, Bérengère, Medina, Anya, Andersson, Lotta, Abels, Mia, Mollet, Inês G., Jain, Deepak, Eliasson, Lena, Wierup, Nils, Fex, Malin, Mulder, Hindrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485242/ https://www.ncbi.nlm.nih.gov/pubmed/28702322 http://dx.doi.org/10.1016/j.molmet.2017.05.005

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