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Tanshinone IIA Inhibits Glutamate-Induced Oxidative Toxicity through Prevention of Mitochondrial Dysfunction and Suppression of MAPK Activation in SH-SY5Y Human Neuroblastoma Cells

Glutamate excitotoxicity is associated with many neurological diseases, including cerebral ischemia and neurodegenerative diseases. Tanshinone IIA, a diterpenoid naphthoquinone from Salvia miltiorrhiza, has been shown to suppress presynaptic glutamate release, but its protective mechanism against gl...

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Detalles Bibliográficos
Autores principales:	Li, Haifeng, Han, Wenjing, Wang, Hongyu, Ding, Fei, Xiao, Lingyun, Shi, Ruona, Ai, Liping, Huang, Zebo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485345/ https://www.ncbi.nlm.nih.gov/pubmed/28690763 http://dx.doi.org/10.1155/2017/4517486

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