Cargando…

Metabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes

Cardiovascular disease is a leading cause of death worldwide. Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) hold immense clinical potential and recent studies have enabled generation of virtually pure hPSC-CMs with high efficiency in chemically defined and xeno-free conditions. Despi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhute, Vijesh J., Bao, Xiaoping, Dunn, Kaitlin K., Knutson, Kylie R., McCurry, Eric C., Jin, Gyuhyung, Lee, Wei-Hua, Lewis, Sarah, Ikeda, Akihiro, Palecek, Sean P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485423/ https://www.ncbi.nlm.nih.gov/pubmed/28656061 http://dx.doi.org/10.7150/thno.19390

Ejemplares similares

Human pluripotent stem cell‐derived epicardial progenitors can differentiate to endocardial‐like endothelial cells
por: Bao, Xiaoping, et al.
Publicado: (2017)

The Poly (ADP-Ribose) Polymerase Inhibitor Veliparib and Radiation Cause Significant Cell Line Dependent Metabolic Changes in Breast Cancer Cells
por: Bhute, Vijesh J., et al.
Publicado: (2016)

(1)H Nuclear magnetic resonance based targeted profiling of metabolic responses induced by DNA damaging agents and PARP inhibition in MCF-7 cells
por: Bhute, Vijesh, et al.
Publicado: (2014)

Engineering Scalable Manufacturing of High-Quality Stem Cell-Derived Cardiomyocytes for Cardiac Tissue Repair
por: Dunn, Kaitlin K., et al.
Publicado: (2018)

Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions
por: Bao, Xiaoping, et al.
Publicado: (2016)

Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling
por: Lian, Xiaojun, et al.
Publicado: (2014)

Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling
por: Lian, Xiaojun, et al.
Publicado: (2015)

Wnt signaling directs human pluripotent stem cells into vascularized cardiac organoids with chamber-like structures
por: Liang, Po-Yu, et al.
Publicado: (2022)

Maturation of pluripotent stem cell derived cardiomyocytes: The new challenge
por: Aigha, Idil, et al.
Publicado: (2016)

Mitochondrial Maturation in Human Pluripotent Stem Cell Derived Cardiomyocytes
por: Dai, Dao-Fu, et al.
Publicado: (2017)

Bioengineering Approaches to Mature Human Pluripotent Stem Cell-Derived Cardiomyocytes
por: Sun, Xuetao, et al.
Publicado: (2017)

Current methods for the maturation of induced pluripotent stem cell-derived cardiomyocytes
por: Machiraju, Pranav, et al.
Publicado: (2019)

Maturation strategies and limitations of induced pluripotent stem cell-derived cardiomyocytes
por: Wu, Peng, et al.
Publicado: (2021)

Using human induced pluripotent stem cell-derived cardiomyocytes to understand the mechanisms driving cardiomyocyte maturation
por: Hamledari, Homa, et al.
Publicado: (2022)

A Small Molecule Inhibitor of Src Family Kinases Promotes Simple Epithelial Differentiation of Human Pluripotent Stem Cells
por: Lian, Xiaojun, et al.
Publicado: (2013)

CAR-neutrophil mediated delivery of tumor-microenvironment responsive nanodrugs for glioblastoma chemo-immunotherapy
por: Chang, Yun, et al.
Publicado: (2023)

Effects of Substrate Mechanics on Contractility of Cardiomyocytes Generated from Human Pluripotent Stem Cells
por: Hazeltine, Laurie B., et al.
Publicado: (2012)

A mutation in transmembrane protein 135 impairs lipid metabolism in mouse eyecups
por: Landowski, Michael, et al.
Publicado: (2022)

Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes
por: Zhu, Renjun, et al.
Publicado: (2014)

Maturation of human pluripotent stem cell derived cardiomyocytes is improved in cardiovascular construct
por: Vuorenpää, Hanna, et al.
Publicado: (2017)

Engineered Maturation Approaches of Human Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes
por: Ge, Feixiang, et al.
Publicado: (2019)

Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
por: Funakoshi, Shunsuke, et al.
Publicado: (2021)

A dual cardiomyocyte reporter model derived from human pluripotent stem cells
por: Jiang, Yuqian, et al.
Publicado: (2021)

Directed Differentiation of Human Pluripotent Stem Cells to Podocytes under Defined Conditions
por: Qian, Tongcheng, et al.
Publicado: (2019)

Biowire: a new platform for maturation of human pluripotent stem cell derived cardiomyocytes
por: Nunes, Sara S., et al.
Publicado: (2013)

Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells: Current Strategies and Limitations
por: Jiang, Yanqing, et al.
Publicado: (2018)

Qualitative transcriptional signatures for evaluating the maturity degree of pluripotent stem cell-derived cardiomyocytes
por: Chen, Rou, et al.
Publicado: (2019)

Fatty Acids Enhance the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells
por: Yang, Xiulan, et al.
Publicado: (2019)

Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Enables Modeling of Human Hypertrophic Cardiomyopathy
por: Knight, Walter E., et al.
Publicado: (2021)

Recent Advances in Maturation of Pluripotent Stem Cell-Derived Cardiomyocytes Promoted by Mechanical Stretch
por: Gu, Xingwang, et al.
Publicado: (2021)

Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells
por: Qian, Tongcheng, et al.
Publicado: (2017)

Activation of AMPK Promotes Maturation of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
por: Ye, Liang, et al.
Publicado: (2021)

A simple protocol to produce mature human-induced pluripotent stem cell-derived cardiomyocytes
por: Knight, Walter E., et al.
Publicado: (2021)

Small molecule-mediated rapid maturation of human induced pluripotent stem cell-derived cardiomyocytes
por: Chirico, Nino, et al.
Publicado: (2022)

Overexpression of KCNJ2 enhances maturation of human-induced pluripotent stem cell-derived cardiomyocytes
por: Zhou, Jingjun, et al.
Publicado: (2023)

Recent advances in regulating the proliferation or maturation of human-induced pluripotent stem cell-derived cardiomyocytes
por: Yang, Hao, et al.
Publicado: (2023)

Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytes
por: Kannan, Suraj, et al.
Publicado: (2023)

BK virus infection and outcome following kidney transplantation in childhood
por: McCaffrey, James, et al.
Publicado: (2021)

In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts
por: Kadota, Shin, et al.
Publicado: (2017)

Polyethylene Terephthalate Textiles Enhance the Structural Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Pekkanen-Mattila, Mari, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9u0nj1shg1rgd7noom096j1nqs