Cargando…
Ataxin-2: From RNA Control to Human Health and Disease
RNA-binding proteins play fundamental roles in the regulation of molecular processes critical to cellular and organismal homeostasis. Recent studies have identified the RNA-binding protein Ataxin-2 as a genetic determinant or risk factor for various diseases including spinocerebellar ataxia type II...
Autores principales: | Ostrowski, Lauren A., Hall, Amanda C., Mekhail, Karim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485521/ https://www.ncbi.nlm.nih.gov/pubmed/28587229 http://dx.doi.org/10.3390/genes8060157 |
Ejemplares similares
-
Conserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeats
por: Ostrowski, Lauren A., et al.
Publicado: (2018) -
Editorial: Non-coding RNA Regulation: Lessons from Model Organisms and Impact on Human Health
por: Mekhail, Karim
Publicado: (2016) -
FOX-2 Dependent Splicing of Ataxin-2 Transcript Is Affected by Ataxin-1 Overexpression
por: Welzel, Franziska, et al.
Publicado: (2012) -
Roles for Non-coding RNAs in Spatial Genome Organization
por: Khosraviani, Negin, et al.
Publicado: (2019) -
Stabilization and Degradation Mechanisms of Cytoplasmic Ataxin-1
por: Kohiyama, Mayumi F., et al.
Publicado: (2016)