Neuroanatomy in mouse models of Rett syndrome is related to the severity of Mecp2 mutation and behavioral phenotypes

BACKGROUND: Rett syndrome (RTT) is a neurodevelopmental disorder that predominantly affects girls. The majority of RTT cases are caused by de novo mutations in methyl-CpG-binding protein 2 (MECP2), and several mouse models have been created to further understand the disorder. In the current literatu...

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Detalles Bibliográficos
Autores principales: Allemang-Grand, Rylan, Ellegood, Jacob, Spencer Noakes, Leigh, Ruston, Julie, Justice, Monica, Nieman, Brian J., Lerch, Jason P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485541/
https://www.ncbi.nlm.nih.gov/pubmed/28670438
http://dx.doi.org/10.1186/s13229-017-0138-8

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