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GRAPE: a pathway template method to characterize tissue-specific functionality from gene expression profiles

BACKGROUND: Personalizing treatment regimes based on gene expression profiles of individual tumors will facilitate management of cancer. Although many methods have been developed to identify pathways perturbed in tumors, the results are often not generalizable across independent datasets due to the...

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Detalles Bibliográficos
Autores principales:	Klein, Michael I., Stern, David F., Zhao, Hongyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485588/ https://www.ncbi.nlm.nih.gov/pubmed/28651562 http://dx.doi.org/10.1186/s12859-017-1711-z

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