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Clinical Implications of Complex Pharmacokinetics for Daratumumab Dose Regimen in Patients With Relapsed/Refractory Multiple Myeloma

New therapeutic strategies are urgently needed to improve clinical outcomes in patients with multiple myeloma (MM). Daratumumab is a first‐in‐class, CD38 human immunoglobulin G1κ monoclonal antibody approved for treatment of relapsed or refractory MM. Identification of an appropriate dose regimen fo...

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Detalles Bibliográficos
Autores principales:	Xu, XS, Yan, X, Puchalski, T, Lonial, S, Lokhorst, HM, Voorhees, PM, Plesner, T, Liu, K, Khan, I, Jansson, R, Ahmadi, T, Ruixo, JJ Perez, Zhou, H, Clemens, PL
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Development
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485722/ https://www.ncbi.nlm.nih.gov/pubmed/27859027 http://dx.doi.org/10.1002/cpt.577

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