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Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation
Recently, aggressive advertisement claimed a “magic role” for plant stem cells in human skin rejuvenation. This review aims to shed light on the scientific background suggesting feasibility of using plant cells as a basis of anti-age cosmetics. When meristem cell cultures obtained from medicinal pla...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485729/ https://www.ncbi.nlm.nih.gov/pubmed/28498360 http://dx.doi.org/10.3390/biom7020040 |
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author | Korkina, Liudmila G. Mayer, Wolfgang de Luca, Chiara |
author_facet | Korkina, Liudmila G. Mayer, Wolfgang de Luca, Chiara |
author_sort | Korkina, Liudmila G. |
collection | PubMed |
description | Recently, aggressive advertisement claimed a “magic role” for plant stem cells in human skin rejuvenation. This review aims to shed light on the scientific background suggesting feasibility of using plant cells as a basis of anti-age cosmetics. When meristem cell cultures obtained from medicinal plants are exposed to appropriate elicitors/stressors (ultraviolet, ultrasound ultraviolet (UV), ultrasonic waves, microbial/insect metabolites, heavy metals, organic toxins, nutrient deprivation, etc.), a protective/adaptive response initiates the biosynthesis of secondary metabolites. Highly bioavailable and biocompatible to human cells, low-molecular weight plant secondary metabolites share structural/functional similarities with human non-protein regulatory hormones, neurotransmitters, pigments, polyamines, amino-/fatty acids. Their redox-regulated biosynthesis triggers in turn plant cell antioxidant and detoxification molecular mechanisms resembling human cell pathways. Easily isolated in relatively large quantities from contaminant-free cell cultures, plant metabolites target skin ageing mechanisms, above all redox imbalance. Perfect modulators of cutaneous oxidative state via direct/indirect antioxidant action, free radical scavenging, UV protection, and transition-metal chelation, they are ideal candidates to restore photochemical/redox/immune/metabolic barriers, gradually deteriorating in the ageing skin. The industrial production of plant meristem cell metabolites is toxicologically and ecologically sustainable for fully “biological” anti-age cosmetics. |
format | Online Article Text |
id | pubmed-5485729 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-54857292017-06-29 Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation Korkina, Liudmila G. Mayer, Wolfgang de Luca, Chiara Biomolecules Review Recently, aggressive advertisement claimed a “magic role” for plant stem cells in human skin rejuvenation. This review aims to shed light on the scientific background suggesting feasibility of using plant cells as a basis of anti-age cosmetics. When meristem cell cultures obtained from medicinal plants are exposed to appropriate elicitors/stressors (ultraviolet, ultrasound ultraviolet (UV), ultrasonic waves, microbial/insect metabolites, heavy metals, organic toxins, nutrient deprivation, etc.), a protective/adaptive response initiates the biosynthesis of secondary metabolites. Highly bioavailable and biocompatible to human cells, low-molecular weight plant secondary metabolites share structural/functional similarities with human non-protein regulatory hormones, neurotransmitters, pigments, polyamines, amino-/fatty acids. Their redox-regulated biosynthesis triggers in turn plant cell antioxidant and detoxification molecular mechanisms resembling human cell pathways. Easily isolated in relatively large quantities from contaminant-free cell cultures, plant metabolites target skin ageing mechanisms, above all redox imbalance. Perfect modulators of cutaneous oxidative state via direct/indirect antioxidant action, free radical scavenging, UV protection, and transition-metal chelation, they are ideal candidates to restore photochemical/redox/immune/metabolic barriers, gradually deteriorating in the ageing skin. The industrial production of plant meristem cell metabolites is toxicologically and ecologically sustainable for fully “biological” anti-age cosmetics. MDPI 2017-05-12 /pmc/articles/PMC5485729/ /pubmed/28498360 http://dx.doi.org/10.3390/biom7020040 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Korkina, Liudmila G. Mayer, Wolfgang de Luca, Chiara Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation |
title | Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation |
title_full | Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation |
title_fullStr | Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation |
title_full_unstemmed | Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation |
title_short | Meristem Plant Cells as a Sustainable Source of Redox Actives for Skin Rejuvenation |
title_sort | meristem plant cells as a sustainable source of redox actives for skin rejuvenation |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485729/ https://www.ncbi.nlm.nih.gov/pubmed/28498360 http://dx.doi.org/10.3390/biom7020040 |
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