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Systematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent prediction
BACKGROUND: The molecular function of a gene is most commonly inferred by sequence similarity. Therefore, genes that lack sufficient sequence similarity to characterized genes (such as certain classes of transcriptional regulators) are difficult to classify using most function prediction algorithms...
Autores principales: | Bossi, Flavia, Fan, Jue, Xiao, Jun, Chandra, Lilyana, Shen, Max, Dorone, Yanniv, Wagner, Doris, Rhee, Seung Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485742/ https://www.ncbi.nlm.nih.gov/pubmed/28651538 http://dx.doi.org/10.1186/s12864-017-3853-9 |
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