A design–build–test cycle using modeling and experiments reveals interdependencies between upper glycolysis and xylose uptake in recombinant S. cerevisiae and improves predictive capabilities of large-scale kinetic models

BACKGROUND: Recent advancements in omics measurement technologies have led to an ever-increasing amount of available experimental data that necessitate systems-oriented methodologies for efficient and systematic integration of data into consistent large-scale kinetic models. These models can help us...

Descripción completa

Detalles Bibliográficos
Autores principales: Miskovic, Ljubisa, Alff-Tuomala, Susanne, Soh, Keng Cher, Barth, Dorothee, Salusjärvi, Laura, Pitkänen, Juha-Pekka, Ruohonen, Laura, Penttilä, Merja, Hatzimanikatis, Vassily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485749/
https://www.ncbi.nlm.nih.gov/pubmed/28674555
http://dx.doi.org/10.1186/s13068-017-0838-5

Ejemplares similares

Ejemplares similares