Formation of Conductive DNA-Based Nanowires via Conjugation of dsDNA with Cationic Peptide

A novel conductive DNA-based nanomaterial, DNA-peptide wire, composed of a DNA core and a peripheral peptide layer, is presented. The electrical conductivity of the wire is found to be at least three orders in magnitude higher than that of native double-stranded DNA (dsDNA). High conductivity of the...

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Autores principales: Nazari, Zeinab Esmail, Gomez Herrero, Julio, Fojan, Peter, Gurevich, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485775/
https://www.ncbi.nlm.nih.gov/pubmed/28556794
http://dx.doi.org/10.3390/nano7060128
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author Nazari, Zeinab Esmail
Gomez Herrero, Julio
Fojan, Peter
Gurevich, Leonid
author_facet Nazari, Zeinab Esmail
Gomez Herrero, Julio
Fojan, Peter
Gurevich, Leonid
author_sort Nazari, Zeinab Esmail
collection PubMed
description A novel conductive DNA-based nanomaterial, DNA-peptide wire, composed of a DNA core and a peripheral peptide layer, is presented. The electrical conductivity of the wire is found to be at least three orders in magnitude higher than that of native double-stranded DNA (dsDNA). High conductivity of the wires along with a better resistance to mechanical deformations caused by interactions between the substrate and electrode surface make them appealing for a wide variety of nanoelectronic and biosensor applications.
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spelling pubmed-54857752017-06-29 Formation of Conductive DNA-Based Nanowires via Conjugation of dsDNA with Cationic Peptide Nazari, Zeinab Esmail Gomez Herrero, Julio Fojan, Peter Gurevich, Leonid Nanomaterials (Basel) Article A novel conductive DNA-based nanomaterial, DNA-peptide wire, composed of a DNA core and a peripheral peptide layer, is presented. The electrical conductivity of the wire is found to be at least three orders in magnitude higher than that of native double-stranded DNA (dsDNA). High conductivity of the wires along with a better resistance to mechanical deformations caused by interactions between the substrate and electrode surface make them appealing for a wide variety of nanoelectronic and biosensor applications. MDPI 2017-05-30 /pmc/articles/PMC5485775/ /pubmed/28556794 http://dx.doi.org/10.3390/nano7060128 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nazari, Zeinab Esmail
Gomez Herrero, Julio
Fojan, Peter
Gurevich, Leonid
Formation of Conductive DNA-Based Nanowires via Conjugation of dsDNA with Cationic Peptide
title Formation of Conductive DNA-Based Nanowires via Conjugation of dsDNA with Cationic Peptide
title_full Formation of Conductive DNA-Based Nanowires via Conjugation of dsDNA with Cationic Peptide
title_fullStr Formation of Conductive DNA-Based Nanowires via Conjugation of dsDNA with Cationic Peptide
title_full_unstemmed Formation of Conductive DNA-Based Nanowires via Conjugation of dsDNA with Cationic Peptide
title_short Formation of Conductive DNA-Based Nanowires via Conjugation of dsDNA with Cationic Peptide
title_sort formation of conductive dna-based nanowires via conjugation of dsdna with cationic peptide
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485775/
https://www.ncbi.nlm.nih.gov/pubmed/28556794
http://dx.doi.org/10.3390/nano7060128
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