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Mammary epithelial polarity and macrophage infiltration
Loss of epithelial cell polarity and inflammation are hallmarks of breast cancer development. Although the association between the disruption of tissue polarity and inflammation has been demonstrated, we know little about how these two events are coupled. Using the 3D co-culture model of mammary epi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485912/ https://www.ncbi.nlm.nih.gov/pubmed/28664188 http://dx.doi.org/10.14800/Macrophage.1521 |
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author | Xu, Ren |
author_facet | Xu, Ren |
author_sort | Xu, Ren |
collection | PubMed |
description | Loss of epithelial cell polarity and inflammation are hallmarks of breast cancer development. Although the association between the disruption of tissue polarity and inflammation has been demonstrated, we know little about how these two events are coupled. Using the 3D co-culture model of mammary epithelial cells and monocytes, a recent study reveals a link between disruption of epithelial polarity and monocytes infiltration. |
format | Online Article Text |
id | pubmed-5485912 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
record_format | MEDLINE/PubMed |
spelling | pubmed-54859122017-06-27 Mammary epithelial polarity and macrophage infiltration Xu, Ren Macrophage (Houst) Article Loss of epithelial cell polarity and inflammation are hallmarks of breast cancer development. Although the association between the disruption of tissue polarity and inflammation has been demonstrated, we know little about how these two events are coupled. Using the 3D co-culture model of mammary epithelial cells and monocytes, a recent study reveals a link between disruption of epithelial polarity and monocytes infiltration. 2017-03-13 2017 /pmc/articles/PMC5485912/ /pubmed/28664188 http://dx.doi.org/10.14800/Macrophage.1521 Text en http://creativecommons.org/licenses/by/4.0/ Licensed under a Creative Commons Attribution 4.0 International License which allows users including authors of articles to copy and redistribute the material in any medium or format, in addition to remix, transform, and build upon the material for any purpose, even commercially, as long as the author and original source are properly cited or credited. |
spellingShingle | Article Xu, Ren Mammary epithelial polarity and macrophage infiltration |
title | Mammary epithelial polarity and macrophage infiltration |
title_full | Mammary epithelial polarity and macrophage infiltration |
title_fullStr | Mammary epithelial polarity and macrophage infiltration |
title_full_unstemmed | Mammary epithelial polarity and macrophage infiltration |
title_short | Mammary epithelial polarity and macrophage infiltration |
title_sort | mammary epithelial polarity and macrophage infiltration |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485912/ https://www.ncbi.nlm.nih.gov/pubmed/28664188 http://dx.doi.org/10.14800/Macrophage.1521 |
work_keys_str_mv | AT xuren mammaryepithelialpolarityandmacrophageinfiltration |