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Mammary epithelial polarity and macrophage infiltration

Loss of epithelial cell polarity and inflammation are hallmarks of breast cancer development. Although the association between the disruption of tissue polarity and inflammation has been demonstrated, we know little about how these two events are coupled. Using the 3D co-culture model of mammary epi...

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Detalles Bibliográficos
Autor principal: Xu, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485912/
https://www.ncbi.nlm.nih.gov/pubmed/28664188
http://dx.doi.org/10.14800/Macrophage.1521
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author Xu, Ren
author_facet Xu, Ren
author_sort Xu, Ren
collection PubMed
description Loss of epithelial cell polarity and inflammation are hallmarks of breast cancer development. Although the association between the disruption of tissue polarity and inflammation has been demonstrated, we know little about how these two events are coupled. Using the 3D co-culture model of mammary epithelial cells and monocytes, a recent study reveals a link between disruption of epithelial polarity and monocytes infiltration.
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spelling pubmed-54859122017-06-27 Mammary epithelial polarity and macrophage infiltration Xu, Ren Macrophage (Houst) Article Loss of epithelial cell polarity and inflammation are hallmarks of breast cancer development. Although the association between the disruption of tissue polarity and inflammation has been demonstrated, we know little about how these two events are coupled. Using the 3D co-culture model of mammary epithelial cells and monocytes, a recent study reveals a link between disruption of epithelial polarity and monocytes infiltration. 2017-03-13 2017 /pmc/articles/PMC5485912/ /pubmed/28664188 http://dx.doi.org/10.14800/Macrophage.1521 Text en http://creativecommons.org/licenses/by/4.0/ Licensed under a Creative Commons Attribution 4.0 International License which allows users including authors of articles to copy and redistribute the material in any medium or format, in addition to remix, transform, and build upon the material for any purpose, even commercially, as long as the author and original source are properly cited or credited.
spellingShingle Article
Xu, Ren
Mammary epithelial polarity and macrophage infiltration
title Mammary epithelial polarity and macrophage infiltration
title_full Mammary epithelial polarity and macrophage infiltration
title_fullStr Mammary epithelial polarity and macrophage infiltration
title_full_unstemmed Mammary epithelial polarity and macrophage infiltration
title_short Mammary epithelial polarity and macrophage infiltration
title_sort mammary epithelial polarity and macrophage infiltration
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485912/
https://www.ncbi.nlm.nih.gov/pubmed/28664188
http://dx.doi.org/10.14800/Macrophage.1521
work_keys_str_mv AT xuren mammaryepithelialpolarityandmacrophageinfiltration