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Increased internalization of complement inhibitor CD59 may contribute to endothelial inflammation in obstructive sleep apnea

Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH) during transient cessation of breathing, triples the risk for cardiovascular diseases. We used a phage display peptide library as an unbiased approach to investigate whether IH, which is specific to OSA, activates endothelial...

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Detalles Bibliográficos
Autores principales: Emin, Memet, Wang, Gang, Castagna, Francesco, Rodriguez-Lopez, Josanna, Wahab, Romina, Wang, Jing, Adams, Tessa, Wei, Ying, Jelic, Sanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485919/
https://www.ncbi.nlm.nih.gov/pubmed/26738794
http://dx.doi.org/10.1126/scitranslmed.aad0634

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