Cargando…

Conformational Flexibility Differentiates Naturally Occurring Bet v 1 Isoforms

The protein Bet v 1 represents the main cause for allergic reactions to birch pollen in Europe and North America. Structurally homologous isoforms of Bet v 1 can have different properties regarding allergic sensitization and Th2 polarization, most likely due to differential susceptibility to proteol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grutsch, Sarina, Fuchs, Julian E., Ahammer, Linda, Kamenik, Anna S., Liedl, Klaus R., Tollinger, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486015/ https://www.ncbi.nlm.nih.gov/pubmed/28587205 http://dx.doi.org/10.3390/ijms18061192

Ejemplares similares

NMR resonance assignments of a hypoallergenic isoform of the major birch pollen allergen Bet v 1
por: Ahammer, Linda, et al.
Publicado: (2017)

Structure of the Major Apple Allergen Mal d 1
por: Ahammer, Linda, et al.
Publicado: (2017)

NMR resonance assignments of the major apple allergen Mal d 1
por: Ahammer, Linda, et al.
Publicado: (2016)

Peptidic Macrocycles - Conformational Sampling and Thermodynamic Characterization
por: Kamenik, Anna S., et al.
Publicado: (2018)

Dynamics Rationalize Proteolytic Susceptibility of the Major Birch Pollen Allergen Bet v 1
por: Kamenik, Anna S., et al.
Publicado: (2020)

Ligand Binding Modulates the Structural Dynamics and Compactness of the Major Birch Pollen Allergen
por: Grutsch, Sarina, et al.
Publicado: (2014)

NMR Methods to Study Dynamic Allostery
por: Grutsch, Sarina, et al.
Publicado: (2016)

Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens
por: Führer, Sebastian, et al.
Publicado: (2021)

pH-Dependent Protonation of the Phl p 6 Pollen Allergen Studied by NMR and cpH-aMD
por: Hofer, Florian, et al.
Publicado: (2019)

Ascorbylation of a Reactive Cysteine in the Major Apple Allergen Mal d 1
por: Ahammer, Linda, et al.
Publicado: (2022)

Longitudinal exchange: an alternative strategy towards quantification of dynamics parameters in ZZ exchange spectroscopy
por: Kloiber, Karin, et al.
Publicado: (2011)

Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen
por: Machado, Yoan, et al.
Publicado: (2016)

Localization of Millisecond Dynamics: Dihedral Entropy from Accelerated MD
por: Kamenik, Anna S., et al.
Publicado: (2016)

Structure and Zeatin Binding of the Peach Allergen Pru p 1
por: Eidelpes, Reiner, et al.
Publicado: (2021)

The Structural Flexibility of PR-10 Food Allergens
por: Führer, Sebastian, et al.
Publicado: (2022)

Thermosensitive Hydration of Four Acrylamide-Based Polymers in Coil and Globule Conformations
por: Quoika, Patrick K., et al.
Publicado: (2020)

Cross-correlated relaxation measurements under adiabatic sweeps: determination of local order in proteins
por: Kadeřávek, Pavel, et al.
Publicado: (2015)

Measurement of Ligand–Target Residence Times by (1)H Relaxation Dispersion NMR Spectroscopy
por: Moschen, Thomas, et al.
Publicado: (2016)

Conformational Ensembles of Antibodies Determine Their Hydrophobicity
por: Waibl, Franz, et al.
Publicado: (2021)

Addressing Challenges of Macrocyclic Conformational Sampling in Polar and Apolar Solvents: Lessons for Chameleonicity
por: Tang, Xuechen, et al.
Publicado: (2023)

Conformational selection of allergen-antibody complexes—surface plasticity of paratopes and epitopes
por: Fernández-Quintero, Monica L, et al.
Publicado: (2019)

NMR resonance assignments of the EVH1 domain of neurofibromin’s recruitment factor Spred1
por: Führer, Sebastian, et al.
Publicado: (2017)

Characterizing the Diversity of the CDR-H3 Loop Conformational Ensembles in Relationship to Antibody Binding Properties
por: Fernández-Quintero, Monica L., et al.
Publicado: (2019)

The Impact of Nitration on the Structure and Immunogenicity of the Major Birch Pollen Allergen Bet v 1.0101
por: Ackaert, Chloé, et al.
Publicado: (2014)

Interrogating the conformational dynamics of BetP transport
por: Robertson, Janice L.
Publicado: (2019)

Folded or Not? Tracking Bet v 1 Conformation in Recombinant Allergen Preparations
por: Husslik, Felix, et al.
Publicado: (2015)

Quantitative Correlation of Conformational Binding Enthalpy with Substrate Specificity of Serine Proteases
por: Waldner, Birgit J., et al.
Publicado: (2015)

Identification of the natural ligand of Bet v 1
por: Seutter von Loetzen, Christian, et al.
Publicado: (2014)

Ligand Recognition of the Major Birch Pollen Allergen Bet v 1 is Isoform Dependent
por: Seutter von Loetzen, Christian, et al.
Publicado: (2015)

A naturally occurring soluble isoform of murine Fas generated by alternative splicing
Publicado: (1995)

A Naturally Occurring Isoform Inhibits Parathyroid Hormone Receptor Trafficking and Signaling
por: Alonso, Verónica, et al.
Publicado: (2011)

Sodium-induced population shift drives activation of thrombin
por: Kahler, Ursula, et al.
Publicado: (2020)

Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S
por: Soh, Wai Tuck, et al.
Publicado: (2017)

Lessons for Oral Bioavailability: How Conformationally Flexible Cyclic Peptides Enter and Cross Lipid Membranes
por: Linker, Stephanie M., et al.
Publicado: (2023)

T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells
por: Kiekens, Laura, et al.
Publicado: (2021)

“Betting on nature” or “betting on others”: anti-coordination induces uniquely high levels of entropy
por: Chierchia, Gabriele, et al.
Publicado: (2018)

Dissection of immunoglobulin E and T lymphocyte reactivity of isoforms of the major birch pollen allergen Bet v 1: potential use of hypoallergenic isoforms for immunotherapy
Publicado: (1996)

NMR resonance assignments of the four isoforms of the hazelnut allergen Cor a 1.04
por: Führer, Sebastian, et al.
Publicado: (2019)

Substrate Sequences Tell Similar Stories as Binding Cavities: Commentary
por: Fuchs, Julian E., et al.
Publicado: (2013)

To Bet or Not to Bet on T-bet As a Therapeutic Target in Emphysema?
por: Wang, Xiaoyun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jcfl4tbfi0dk8863gioslhb921