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Emerging Role of the Spleen in the Pharmacokinetics of Monoclonal Antibodies, Nanoparticles and Exosomes

After being absorbed, drugs distribute in the body in part to reach target tissues, in part to be disposed in tissues where they do not exert clinically-relevant effects. Therapeutically-relevant effects are usually terminated by drug metabolism and/or elimination. The role that has been traditional...

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Detalles Bibliográficos
Autores principales: Cataldi, Mauro, Vigliotti, Chiara, Mosca, Teresa, Cammarota, MariaRosaria, Capone, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486072/
https://www.ncbi.nlm.nih.gov/pubmed/28604595
http://dx.doi.org/10.3390/ijms18061249