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Eplerenone-Resistant Salt-Sensitive Hypertension in Nedd4-2 C2 KO Mice

The epithelial sodium channel (ENaC) plays critical roles in maintaining fluid and electrolyte homeostasis and is located in the aldosterone-sensitive distal nephron (ASDN). We previously found that Nedd4-2 C2 knockout (KO) mice showed salt-sensitive hypertension with paradoxically enhanced ENaC gen...

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Detalles Bibliográficos
Autores principales:	Kino, Tabito, Ishigami, Tomoaki, Murata, Tsumugi, Doi, Hiroshi, Nakashima-Sasaki, Rie, Chen, Lin, Sugiyama, Michiko, Azushima, Kengo, Wakui, Hiromichi, Minegishi, Shintaro, Tamura, Kouichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486073/ https://www.ncbi.nlm.nih.gov/pubmed/28604611 http://dx.doi.org/10.3390/ijms18061250

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