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Association between Air Pollution and Emergency Room Visits for Atrial Fibrillation

Despite the large prevalence in the population, possible factors responsible for the induction of atrial fibrillation (AF) events in susceptible individuals remain incompletely understood. We investigated the association between air pollution levels and emergency department admissions for AF in Rome...

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Autores principales: Solimini, Angelo G., Renzi, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486347/
https://www.ncbi.nlm.nih.gov/pubmed/28632149
http://dx.doi.org/10.3390/ijerph14060661
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author Solimini, Angelo G.
Renzi, Matteo
author_facet Solimini, Angelo G.
Renzi, Matteo
author_sort Solimini, Angelo G.
collection PubMed
description Despite the large prevalence in the population, possible factors responsible for the induction of atrial fibrillation (AF) events in susceptible individuals remain incompletely understood. We investigated the association between air pollution levels and emergency department admissions for AF in Rome. We conducted a 14 years’ time-series study to evaluate the association between the daily levels of air pollution (particulate matter, PM(10) and PM(2.5), and nitrogen dioxide, NO(2)) and the daily count of emergency accesses for AF (ICD-9 code: 427.31). We applied an over-dispersed conditional Poisson model to analyze the associations at different lags after controlling for time, influenza epidemics, holiday periods, temperature, and relative humidity. Additionally, we evaluated bi-pollutant models by including the other pollutant and the influence of several effect modifiers such as personal characteristics and pre-existing medical conditions. In the period of study, 79,892 individuals were admitted to the emergency departments of Rome hospitals because of AF (on average, 15.6 patients per day: min = 1, max = 36). Air pollution levels were associated with increased AF emergency visits within 24 h of exposure. Effect estimates ranged between 1.4% (0.7–2.3) for a 10 µg/m(3) increase of PM(10) to 3% (1.4–4.7) for a 10 µg/m(3) increase of PM(2.5) at lag 0–1 day. Those effects were higher in patients ≥75 years for all pollutants, male patients for PM(10), and female patients for NO(2). The presence of previous cardiovascular conditions, but not other effect modifiers, increase the pollution effects by 5–8% depending on the lag. This study found evidence that air pollution is associated with AF emergency visits in the short term.
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spelling pubmed-54863472017-06-30 Association between Air Pollution and Emergency Room Visits for Atrial Fibrillation Solimini, Angelo G. Renzi, Matteo Int J Environ Res Public Health Article Despite the large prevalence in the population, possible factors responsible for the induction of atrial fibrillation (AF) events in susceptible individuals remain incompletely understood. We investigated the association between air pollution levels and emergency department admissions for AF in Rome. We conducted a 14 years’ time-series study to evaluate the association between the daily levels of air pollution (particulate matter, PM(10) and PM(2.5), and nitrogen dioxide, NO(2)) and the daily count of emergency accesses for AF (ICD-9 code: 427.31). We applied an over-dispersed conditional Poisson model to analyze the associations at different lags after controlling for time, influenza epidemics, holiday periods, temperature, and relative humidity. Additionally, we evaluated bi-pollutant models by including the other pollutant and the influence of several effect modifiers such as personal characteristics and pre-existing medical conditions. In the period of study, 79,892 individuals were admitted to the emergency departments of Rome hospitals because of AF (on average, 15.6 patients per day: min = 1, max = 36). Air pollution levels were associated with increased AF emergency visits within 24 h of exposure. Effect estimates ranged between 1.4% (0.7–2.3) for a 10 µg/m(3) increase of PM(10) to 3% (1.4–4.7) for a 10 µg/m(3) increase of PM(2.5) at lag 0–1 day. Those effects were higher in patients ≥75 years for all pollutants, male patients for PM(10), and female patients for NO(2). The presence of previous cardiovascular conditions, but not other effect modifiers, increase the pollution effects by 5–8% depending on the lag. This study found evidence that air pollution is associated with AF emergency visits in the short term. MDPI 2017-06-20 2017-06 /pmc/articles/PMC5486347/ /pubmed/28632149 http://dx.doi.org/10.3390/ijerph14060661 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Solimini, Angelo G.
Renzi, Matteo
Association between Air Pollution and Emergency Room Visits for Atrial Fibrillation
title Association between Air Pollution and Emergency Room Visits for Atrial Fibrillation
title_full Association between Air Pollution and Emergency Room Visits for Atrial Fibrillation
title_fullStr Association between Air Pollution and Emergency Room Visits for Atrial Fibrillation
title_full_unstemmed Association between Air Pollution and Emergency Room Visits for Atrial Fibrillation
title_short Association between Air Pollution and Emergency Room Visits for Atrial Fibrillation
title_sort association between air pollution and emergency room visits for atrial fibrillation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486347/
https://www.ncbi.nlm.nih.gov/pubmed/28632149
http://dx.doi.org/10.3390/ijerph14060661
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