Cargando…
Relationship between normal tension glaucoma and Flammer syndrome
BACKGROUND: Besides intraocular pressure, vascular factors play a role in the pathogenesis of glaucomatous optic neuropathy. One of these potential vascular factors is Flammer syndrome. The purpose of the present study was to determine in a Korean population whether signs and symptoms of Flammer syn...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486531/ https://www.ncbi.nlm.nih.gov/pubmed/28725291 http://dx.doi.org/10.1007/s13167-017-0097-3 |
_version_ | 1783246270926684160 |
---|---|
author | Konieczka, Katarzyna Choi, Hyuk Jin Koch, Simone Fankhauser, Franz Schoetzau, Andreas Kim, Dong Myung |
author_facet | Konieczka, Katarzyna Choi, Hyuk Jin Koch, Simone Fankhauser, Franz Schoetzau, Andreas Kim, Dong Myung |
author_sort | Konieczka, Katarzyna |
collection | PubMed |
description | BACKGROUND: Besides intraocular pressure, vascular factors play a role in the pathogenesis of glaucomatous optic neuropathy. One of these potential vascular factors is Flammer syndrome. The purpose of the present study was to determine in a Korean population whether signs and symptoms of Flammer syndrome occur more often in normal tension glaucoma patients than in control subjects. METHODS: Two hundred forty-six normal tension glaucoma patients and 1116 control subjects responded to a multiple-choice questionnaire asking about 15 signs and symptoms of Flammer syndrome. RESULTS: Seven of the 15 signs and symptoms of Flammer syndrome (increased drug sensitivity, good smell perception, reversible skin blotches, tinnitus, long sleep onset time, tendency to perfectionism, and cold hands/feet) were significantly more often positive in normal tension glaucoma patients than in controls. Six additional signs and symptoms (migraines, low blood pressure, headaches, dizziness, increased pain sensation, and feeling cold) also occurred more often, but did not reach statistical significance. Only two items (low body weight and reduced feeling of thirst) were more frequently (not significant) positive in the controls. CONCLUSION: There is an association between normal tension glaucoma and Flammer syndrome. If future studies confirm this relationship, treatment of Flammer syndrome may help to prevent normal tension glaucoma or to slow down its progression. |
format | Online Article Text |
id | pubmed-5486531 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-54865312017-07-17 Relationship between normal tension glaucoma and Flammer syndrome Konieczka, Katarzyna Choi, Hyuk Jin Koch, Simone Fankhauser, Franz Schoetzau, Andreas Kim, Dong Myung EPMA J Research BACKGROUND: Besides intraocular pressure, vascular factors play a role in the pathogenesis of glaucomatous optic neuropathy. One of these potential vascular factors is Flammer syndrome. The purpose of the present study was to determine in a Korean population whether signs and symptoms of Flammer syndrome occur more often in normal tension glaucoma patients than in control subjects. METHODS: Two hundred forty-six normal tension glaucoma patients and 1116 control subjects responded to a multiple-choice questionnaire asking about 15 signs and symptoms of Flammer syndrome. RESULTS: Seven of the 15 signs and symptoms of Flammer syndrome (increased drug sensitivity, good smell perception, reversible skin blotches, tinnitus, long sleep onset time, tendency to perfectionism, and cold hands/feet) were significantly more often positive in normal tension glaucoma patients than in controls. Six additional signs and symptoms (migraines, low blood pressure, headaches, dizziness, increased pain sensation, and feeling cold) also occurred more often, but did not reach statistical significance. Only two items (low body weight and reduced feeling of thirst) were more frequently (not significant) positive in the controls. CONCLUSION: There is an association between normal tension glaucoma and Flammer syndrome. If future studies confirm this relationship, treatment of Flammer syndrome may help to prevent normal tension glaucoma or to slow down its progression. Springer International Publishing 2017-06-02 /pmc/articles/PMC5486531/ /pubmed/28725291 http://dx.doi.org/10.1007/s13167-017-0097-3 Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Research Konieczka, Katarzyna Choi, Hyuk Jin Koch, Simone Fankhauser, Franz Schoetzau, Andreas Kim, Dong Myung Relationship between normal tension glaucoma and Flammer syndrome |
title | Relationship between normal tension glaucoma and Flammer syndrome |
title_full | Relationship between normal tension glaucoma and Flammer syndrome |
title_fullStr | Relationship between normal tension glaucoma and Flammer syndrome |
title_full_unstemmed | Relationship between normal tension glaucoma and Flammer syndrome |
title_short | Relationship between normal tension glaucoma and Flammer syndrome |
title_sort | relationship between normal tension glaucoma and flammer syndrome |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486531/ https://www.ncbi.nlm.nih.gov/pubmed/28725291 http://dx.doi.org/10.1007/s13167-017-0097-3 |
work_keys_str_mv | AT konieczkakatarzyna relationshipbetweennormaltensionglaucomaandflammersyndrome AT choihyukjin relationshipbetweennormaltensionglaucomaandflammersyndrome AT kochsimone relationshipbetweennormaltensionglaucomaandflammersyndrome AT fankhauserfranz relationshipbetweennormaltensionglaucomaandflammersyndrome AT schoetzauandreas relationshipbetweennormaltensionglaucomaandflammersyndrome AT kimdongmyung relationshipbetweennormaltensionglaucomaandflammersyndrome |