Pathogenic implications of distinct patterns of iron and zinc in chronic MS lesions

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) in which oligodendrocytes, the CNS cells that stain most robustly for iron and myelin are the targets of injury. Metals are essential for normal CNS functioning, and metal imbalances have been...

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Detalles Bibliográficos
Autores principales: Popescu, Bogdan F., Frischer, Josa M., Webb, Samuel M., Tham, Mylyne, Adiele, Reginald C., Robinson, Christopher A., Fitz-Gibbon, Patrick D., Weigand, Stephen D., Metz, Imke, Nehzati, Susan, George, Graham N., Pickering, Ingrid J., Brück, Wolfgang, Hametner, Simon, Lassmann, Hans, Parisi, Joseph E., Yong, Guo, Lucchinetti, Claudia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486634/
https://www.ncbi.nlm.nih.gov/pubmed/28332093
http://dx.doi.org/10.1007/s00401-017-1696-8

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