Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection

BACKGROUND: Polyclonal B-cell activation is well known to occur in Plasmodium infections, but its role in pathogenesis or protection remains unclear. However, protective properties of natural antibodies have previously been demonstrated in other contexts. METHODS: Sera from asymptomatic and symptoma...

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Detalles Bibliográficos
Autores principales: Fesel, Constantin, Goulart, Luis F, Silva Neto, Adolfo, Coelho, Alysson, Fontes, Cor Jesus F, Braga, Erika M, Vaz, Nelson M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548665/
https://www.ncbi.nlm.nih.gov/pubmed/15661070
http://dx.doi.org/10.1186/1475-2875-4-5

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